Thursday, January 19, 2006

Vietnam: H5N1 Resistance to Tamiflu

A small case series from Vietnam has highlighted oseltamivir resistance in Influenza A (H5N1) virus. With the inexorable march of avain flu westwards and the continuing deaths it is causing, the New England Journal of Medicine published this sobering case series recently.

The paper describes the outcomes of eight Veitnamese patients who were infected with Influenza A (H5N1) virus and who received oseltamivir as treatment. The surviving patients had rapid declines in the viral load to undetectable levels during treatment. The patients who died with oseltamivir resistant strains however showed increased viral RNA loads in throat swabs. Read More ....

Source: Fleming Forum
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